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Scleral Melanocytosis Dangerous. Louwagie CR1 Baratz KH Pulido JS Salomo DR Dierks DL. Nevus complexion associated melanosis PAM melanoma. The hypothesis that ocular melanocytosis is a precancerous condition that may lead to a choroidal melanoma should be seriously questioned for the following reasons. SM was found in 49 of boys and 41 of girls under the age of 1 year.
It involves congenital hyperpigmentation of the tissue due to an excessive accumulation of melanocyte cells in this part of the eye. The incidence of malignant degeneration in a hyperpigmented eye is unknown and overreported. The sclera like the cornea contains a basal endothelium above which there is the lamina fusca containing a high count of pigment cells. The nevus is located in the deep episclera sclera and uveal tract and can manifest clinically as iris heterochromia patchy slate-gray or bluish discoloration of the sclera and increased pigmentation of the ipsilateral fundus. Episcleral melanoma as a complication of ocular melanocytosis. Oculodermal melanocytosis ODM also known as nevus of Ota is a congenital pigmentary abnormality in the periocular region characterized by excessive melanocytes.
Lodermal melanocytosis are at higher risk for choroidal melanomas -Gonioscopy.
If the hypothesis were correct a bilateral melanoma would occasionally occur in patients. Louwagie CR1 Baratz KH Pulido JS Salomo DR Dierks DL. Oculodermal melanocytosis is discussed under the subject of pigmented lesions of the eyelids. 2532020 Scleral melanocytosis amelanotic conjunctival nevi and scleral thinning are three eye conditions associated with gray spots on the whites of eyes explains EyeSmart. Describe pertinent clinical features. The middle thickest layer is also called the stroma.